| COMPANY | DRUG | Research | Preclin | Phase 1 | Phase 2 | Phase 3 | NDA |
| Vertex |
Telaprevir (VX-950) Protease Inhibitor |
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| Vertex |
VX-500 protease inhibitor | ||||||
| Vertex |
VX-813 2nd gen protease inhibitor |
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| Schering |
Boceprevir (SCH503034) Protease inhibitor |
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| Intermune / Roche |
Protease inhibitor ITMN-191 R7227 |
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| Intermune |
2nd Gen. Protease inhibitor | ||||||
| Roche / Pharmasset |
R7128 nucleoside polymerase inhibitor |
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| Roche / Medivir |
HCV polymerase inhibitor |
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| Medivir / Tibotec |
TMC435 Protease inhibitor | ||||||
| Medivir / Tibotec |
polymerase inhibitor |
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| Pfizer |
PF-868554 Non-Nuc Polymerase inhibitor |
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| Pfizer |
PF-4878691 |
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| Benitec / Tacere Bio / Pfizer |
RNA interference TT033 |
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| Boehringer Ingelheim |
BI 201335 protease inhibitor |
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| Boehringer Ingelheim |
BI 207127 Polymerase inhib. |
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| Intercell Novartis |
IC41 Therapeutic Vacccine | ||||||
| Chiron / CSL |
Therapeutic Vaccine CSL123 |
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| Bristol-Myers Squibb |
BMS-790052 NS5A Inhibitor |
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| Bristol-Myers Squibb |
BMS-791325 Protease inhibitor |
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| Bristol-Myers Squibb |
BMS-650032 NS3 Inhibitor |
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| Bristol-Myers Squibb |
BMS-824393 |
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| Merck |
MK-7009 protease inhibitor |
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| Sirna Therapeutics (aquired by Merck) |
SIRNA-034 RNAi RNA interference |
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| Isis / Merck |
MK-0608 nucleoside polymerase inhib. |
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| Anadys |
ANA598 Polymerase inhib |
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| ViroChem Pharma (acquired by Vertex) |
VCH-759 Non nuc Polymerase inhib |
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| ViroChem Pharma |
Polymerase inhib |
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| ViroChem Pharma |
Polymerase inhib |
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| Globeimmune |
GI 5005 Therapeutic Vaccine |
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| iTherX (formerly Immusol) |
ITX5061 Entry Inhibitor | ||||||
| iTherX |
ITX4520 Entry Inhibitor |
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| Idenix |
IDX184 Nucleoside Polymerase Inhibitor |
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| Idenix |
Protease Inhibitors IDX136&316 |
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| Idenix |
Non-Nuc Polymerase Inhibitor IDX375 |
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| Abbott |
A-837093 Non-nuc polymerase inhib |
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| Gilead |
GS 9190 non-nuc polymerase inhibitor |
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| Gilead / Achillion |
ACH-1095 Protease inhibitor |
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| Gilead |
Protease polymerase inhib |
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| Presidio |
PPI-461 NS5A inhibitor |
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| Achillion |
ACH-1625 Protease inhibitor |
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| Aethlon Medical |
Hemopurifier |
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| Transgene |
TG4040 (MVA-HCV) Therapeutic Vaccine |
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| Tripep / Inovio |
Therapeutic Vaccine Chronvac-C |
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| Arrow Therapeutics (aquired by AstraZeneca) |
A-831 NS5A inhibitor | ||||||
| Arrow Therapeutics |
A-689 NS5A Inhibitor |
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| U of Mass. Med School |
MBL-HCV1 human monoclonal antibody |
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| Eiger BioPharmaceuticals |
NS4B-RNA Binding Inhibitor |
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| GENimmune (subsidiary of Innogenetics) |
GNI-103 – Therapeutic vaccine |
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| GENimmune |
GNI-104 - monoclonal antibodie E1 protein |
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| ChemDiv / IDialog |
ID-12 small molecule | ||||||
| Biocryst |
Polymerase inhibitor |
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| Genelabs GL59728 & GL60667 |
Non-nucleoside & nucleoside polymerase inhib. |
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| Genelabs |
NS5a NS4b & Replicase inhibitors | ||||||
| ViRex Medical |
Hepavaxx C Therapeutic Vaccine |
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| GenPhar |
Vaccine |
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| Genmab |
HuMax-HepC antibody |
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| Abbott / Enanta |
ABT-450 Protease inhib | ||||||
| Pharmasset |
PSI-7851 nucleoside polymerase inhib. |
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| Inhibitex |
INX08189 Polymerase inhibitor |
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| Pharmasset |
PSI-938 nucleoside polymerase inhib. |
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| Enanta |
Polymerase Inhibitor |
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| Enanta |
Cyclophilin binder |
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| Dynavax |
Immunostimulatory sequences Type C TLR9 agonist |
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| Protiva Biotherapeutics |
siRNA |
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| Phenomix |
PHX1766 protease inhibitor | ||||||
| Phenomix |
protease inhibitor |
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| Phenomix |
Polymerase Inhibitor |
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| Samaritan Pharmaceuticals |
SP-30 entry inhibitor |
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| Presidio (aquired from XTL ) |
NS5A inhibitors |
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| Avila Therapeutics |
AVL-181 protease inhibitor |
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| Altor BioScience |
Soluble T-cell Antigen Receptor |
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| Arisyn Therapeutics |
ATI-0810 (Formerly PG301029) RNA and protein production inhibitor |
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| Progenics |
PRO 206 entry inhibitor |
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| Migenix |
N-nucleoside Poly inhib |
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| Merck / Metabasis |
Polymerase inhib small molecule |
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| PTC / Schering |
IRES inhib |
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| Vertex |
Helicase inhibitor |
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| Medivir / Roche |
Polymerase inhibor | ||||||
| Cetek |
small molecule |
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| Itherx (Immusol)/ Novartis |
ITX2155 l |
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| Argos Therapeutics |
Therapeutic Vaccine | ||||||
| Tibotec |
Polymerase inhib. | ||||||
| Regulus Therapeutics (Alnylam / Isis) |
microRNA antagonism of miR-122 host gene |
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| CombiMatrix |
RNAi | ||||||
| Arrow Therapeutics |
Polymerase inhibitor |
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| Boehringer Ingelheim / Biota |
Nucleoside analogues |
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| BioLeap |
???? |
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| Alios BioPharma |
Small Molecule Antivirals |
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| Biotron |
targeting HCV-p7 |
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| NanoViricides |
HepaCide-I |
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| Hanall |
Antihepatitis agents |
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| Astex Therapeutics |
Enzyme Inhibitor | ||||||
| Avexa / TargetDrug |
replication inhib. |
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| StemCells Inc |
HCV resistant Human liver engrafting cells |
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| COMPANY | DRUG | Research | Preclin | Phase 1 | Phase 2 | Phase 3 | NDA |
| Human Genome Sciences |
Albuferon (interferon / albuminfusion) |
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| SciClone Pharma / Sigmatau |
Zadaxin - thymalfasin |
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| SciClone Pharma |
SCV-07 immunomodulator |
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| Migenix |
MX3235 Celgosivir alpha-glucosidase I inhibitor |
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| Intarcia |
Omega Interferon | ||||||
| NABI |
Polyclonal antibody Civacir |
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| Bioenvision |
Suvus | ||||||
| Transition Therapeutics |
IET Interferon Enhancing Therapy |
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| Romark Laboratories |
Alinia | ||||||
| Biolex / OctoPlus |
Locteron controlled release interferon |
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| Kemin Pharma |
KPE02003002 |
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| VioQuest Pharmaceuticals |
Lenocta (sodium stibogluconate SSG) |
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| Conatus |
CTS-1027 MMP inhibitor |
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| Jenkin |
JKB-122 antiinflammatory |
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| Oklahoma University Health Sciences Center |
Fluvastatin |
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| Antipodean |
Mito-Q antiinflammatory |
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| Phynova |
PYN17 antiviral anti-inflammatory anti-fibrotic |
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| Canopus |
CB5300 antiviral |
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| Medtronic |
continuous subcutaneous interferon external pump infusion system |
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| Phynova |
PYN18 anti viral plant extract |
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| Can-Fite |
CF102 antiinflammatory |
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| Biotron |
BIT225 | ||||||
| Peregrine Pharm |
Bavituximab | ||||||
| Enzo Biochem |
Immune Regulator ECH18 |
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| Immunomedics |
IMMU 105 | ||||||
| Amarillo Bioscience / CytoPharm |
Low Dose Oral Interferon | ||||||
| Bristol-Myers Squibb (was owned by ZymoGenetics) |
PEG-Interferon lambda | ||||||
| Novelos |
NOV-205 immunomodulating and antiinflammatory |
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| Scynexis |
SCY-635 | ||||||
| Idera |
IMO-2125 TLR9 Agonist |
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| Anadys |
ANA773 TLR7 agonist |
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| Debiopharm |
Debio 025 Cyclophilin Inhibitor |
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| Medarex / Ono |
MDX-1106 (ONO-4538) anti-PD1 |
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| Cytheris |
CYT107 Interleukin-7 |
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| Cubist |
CB-183872 Protein therapeutic - Formerly IB657 (Illumigen Biosciences) |
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| Kemin Pharma |
KPE00001133 |
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| REPLICor |
REP 9C broad-spectrum entry inhibitor |
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| Nautilus |
Oral Belerofon |
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| Anadys |
AN 025-1 |
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| Genodyssee |
GEA007.1 IFN alpha variant |
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